Advances in 4D Radiation Therapy for Managing Respiration Part II 4D
4D imaging for target definition in stereotactic radiotherapy for lung
Comparative evaluation of CTbased and PET4DCTbased planning target
T2Weighted 4D Magnetic Resonance Imaging for Application in Magnetic
Advances in 4D radiation therapy for managing respiration Part II 4D
4Dimensional Imaging for Radiation Oncology A Clinical Springer
Purpose To compare planning target volume PTV defined by PET combined with 4DCT to 3DCT and 4DCT Methods Eighteen 1830 esophageal cancer patients who underwent 3DCT 4DCT and 18 FFDG PETCT thoracic simulation with SUV max 20 of the primary volume were enrolled CTV 3D was formed on 3DCT by adding a margin of 30 mm in cranialcaudal direction and 5 mm in transversal direction
PDF Canadian Partnership for Quality Radiotherapy CPQR
Full Rtp 4d Target
Consequently 4DCTinformed motion management based on 4DCT simulation became a hot topic 7 Indeed for the first time we had a 4D radiotherapy treatment planning RTP tool providing a patientspecific 3D targetmotion estimation
The difference between 3D virtual simulation workstations and full RTP systems is the dose calculation and dose evaluation capabilities that are integral with the latter The process of CT The encompassing volume of a target can then be produced from a 4DCT dataset providing an accurate representation of the tumour volume
Designing a radiotherapy treatment plan RTP for lung and abdominal cancer is challenging due to the motion of the abdominalthoracic region 1 An appropriate RTP should deliver the prescribed dose to the target and minimize dose to radiosensitive healthy structures Unlike conventional free breathing scans where generic margins are added 4dimensional 4D images provide information on
The overall goal of 4D RTP is no different than for 3D RTP maximize the therapeutic ratio by delivering high doses to the tumor while minimizing doses to normal tissues and organs at risk 2The chief prerequisite for achieving this goal is the accurate definition of tumors and normal tissues dose conformality is a close second and a direct consequence of the first prerequisite
Background To assess the feasibility and potential impact on target delineation of respiratorygated 4D contrastenhanced 18Fluorine fluorodeoxyglucose FDG positron emission tomography computed tomography PETCT in the treatment planning position for a prospective cohort of patients with lower third oesophageal cancer Methods Fifteen patients were recruited into the study Imaging
PETCT imaging for target volume delineation in curative intent
Full Rtp 4d Target
Thus the Internal Target Volume ITVbased approach for RTP leveraged this more explicit ITV significantly reducing either a populationbased 3D margin expansion or an envelope based on multiple
4DCT is long overdue for improvement PMC PubMed Central PMC
Respiratorygated 4D contrastenhanced FDG PETCT for radiotherapy
A number of techniques have been used to generate RTP target volumes using the information gleaned from PET and CT this GTV may also include the full motion path of all tumor locations to create a respiration expanded GTV reGTV Using 4D PETCT imaging may lead to better quantification of tumor motion during prolonged radiotherapy
The overall goal of 4D RTP is no different than for 3D RTP such an involved procedure Finally yet importantly as already stated on several occasions the clinical benefit of full 4D RT is still unknown and perhaps questionable The target that meets the requirement of being the envelope of all tumor locations is the previously defined
These contours can be combined on the fulllength scan which is used for treatment planning to generate an internal target volume ITV In this section we discuss target delineation GTV and ITV in 4D RTP based on 4D CT images In many of the the following examples relating to studies carried out for the treatment of early stage lung